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This is issue 242, Vol. IV of this newspaper, No. 242. This file is 8 pages long and is written in English. Several sample headlines include: "Cure for Small Pox" and "Boston Jubilee".
The image is a piece of article talking about Chile's smallpox epidemic and a possible cure proposed by a doctor. The image is located in the Valparaiso and West Coast Mail, issue No. 242, Vol. IV, August 03, 1872.